Microplastics attack the brain: researchers uncover the invisible danger
Researchers have recently uncovered evidence suggesting microplastics can infiltrate and damage the brain through multiple mechanisms. A key study identifies five primary pathways of harm, linking these particles to potential risks for neurodegenerative diseases like Alzheimer’s and Parkinson’s.
Microplastics trigger immune cell activation, heighten oxidative stress by elevating reactive oxygen species, and weaken the blood-brain barrier, allowing easier entry into brain tissue. They also impair mitochondrial energy production, reducing ATP supply critical for neuron function, and cause direct neuronal damage, with these effects amplifying each other.
Exposure may accelerate beta-amyloid plaque buildup in Alzheimer’s models and harm dopaminergic neurons tied to Parkinson’s, as shown in animal studies with nanoplastics. Human brain samples reveal rising microplastic levels, up 50% in recent years, with dementia cases showing far higher concentrations.
Limiting plastic use in food packaging, clothing, and cosmetics helps curb intake, as microplastics enter via ingestion, inhalation, and bloodstream. Health authorities urge further research and policy action given detections in human tissues.
